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T cells were effectively expanded following activation with a T-cell activator (SailyBio in-house product: XY Beads).
Figure: T-cell proliferation data following activation with the T-cell activator (XY Beads)
T cells primarily mediate cellular immunity and regulate the body's immune response; the T-cell immune response is the most important host response controlling tumor growth and development. Immunosuppression within the tumor microenvironment leaves CD8+ T cells (hereinafter referred to as CTLs, i.e., tumor-killing T cells) in a state of immune exhaustion. Activating CTLs and maintaining T-cell function within the tumor microenvironment is a key objective of cancer immunotherapy.
SailyBio provides a stable and reliable T-cell activation and expansion service and holds proprietary intellectual property rights to its CD3/CD28 activation magnetic beads, which can optimize in vitro T-cell activation and proliferation in translational research and immunotherapy while preserving T-cell viability and immune function.
SailyBio's T-cell activation and expansion service effectively achieves T-cell expansion and in vitro activation, and is applicable to cancer immunotherapy, CAR-T/T-cell therapy process development, and in vitro immunology research. Alternative activation protocols such as PHA are also available to meet the requirements of different experimental systems.
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