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After 12 days of activation, γδ T cells can be expanded more than 400-fold, reaching purity above 91%.
γδ T cells activated and expanded for 12 days were co-incubated with K562 cells at different ratios; all groups produced marked killing of K562 cells in a dose-dependent manner.
Figure: γδ T cell expansion data (>400-fold expansion over 12 days)
Figure: γδ T cell killing data against K562 cells
γδ T cells are T cells that perform innate immune functions, and their TCR is composed of γ and δ chains. SailyBio provides a stable and reliable γδ T cell activation and expansion service, which enables large-scale expansion of γδ T cells from PBMCs with high expansion efficiency and a high percentage of target cells. After 12 days of culture, the total number of γδ T cells derived from PBMCs can be expanded by at least 400-fold, with γδ T cell purity exceeding 90%. This provides strong support for the use of γδ T cells in preclinical research.
SailyBio's γδ T cell activation and expansion service: after 12 days of PBMC culture, γδ T cells expand more than 400-fold with purity above 90%; the activated and expanded γδ T cells can be used for K562 killing assay validation, providing strong support for preclinical γδ T cell therapy research and innate immune T cell research.