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Industrialized cell isolation and preparation workflows with full-process quality control management.
Stable and compliant immune cell sourcing shortens experimental cycles and ensures consistency of conclusions.
Based on a donor pool of more than 2,000 donors, donors with stronger immune responses can be pre-screened, accelerating development and reducing R&D costs.
Safe and compliant project services that satisfy the compliance documentation requirements for new drug application regulatory submissions.
Macrophages (M2) are used as effector cells and Raji cells as target cells.
CD47 and CD20 antibodies induce macrophages to exert ADCP in a dose-dependent manner.
Figure: CD47/CD20 antibody-
The ADCP assay is a very important component of antibody pharmacodynamic evaluation and represents a mature and robust assay system for macrophage induction and phagocytosis experiments.
SailyBio's ADCP assay service centers on macrophage phagocytosis to systematically evaluate the antibody-dependent cellular phagocytosis function of antibodies, supporting the efficacy evaluation of antibody drugs targeting CD47, CD20, and other targets. Case data demonstrate that CD47/CD20 antibodies mediate macrophage phagocytosis in a dose-dependent manner.
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